Multiple Meningioma: Case Report

Despite of their frequent occurrence among the brain tumor, meningiomas are rarely seen as a multiple growth. Most authors report an incidence ranging from 1 to 3% of all meningioma prior to the introduction of computed tomography. After the CT has introduced, diagnostic problems involved with multiple meningiomas were resolved, and its reported incidence was arisen to 8~8.9% of all meningiomas. It may be difficult to differenciate multiple meningioma from the special varient(forme fruste) of von Recklinghausen's disease. Although the pathogenetic factors related to the multiple meningiomas are unknown, various theories of the etiology have been studied and reported. We report a patient with multiple meningioma without evidence of von Recklinghausen's diseases.

A Case of Chondroma in Middle Cranial Fossa: Case Report

Intracranial chondromas are extremely rare tumors, but when present, are generally related to the synchondrosis of the base, and they have several distinct features. They are slow growing benign tumors, and plain roentgenogram frequently reveals lytic lesion and stippled calcification at base of the skull. They are radioresistant, and surgical removal is treatment of choice. We report the rare case of chondroma arisen from base of the skull which diagnosed by brain CT and confirmed by operation.

Atypical C-T Features of Intracranial Meningiomas and Pathological Correlation

Most intracranial meningiomas present on the C-T as typical features with homogeneous, occasionally lobulated mass of density equal or greater than of surrounding brain tissue. After contrast injection, there is uniform and homogeneous enhancement in the density. Infrequently a significant number present as atypical features which are regional inhomogenecity of tumor mass on C-T and common source of error in the diagnosis of meningioma. The authors reviewed 25 consecutive meningiomas, all confirmed pathologically. 7 cases have been encountered as atypical features on the C-T. Among them, 2 cases of peritumoral low density were diagnosed as meningioma with C-T only. 5 cases(2 cases of peritumoral cyst, 2 cases of intratumoral cyst, 1 case of peritumoral bleeding) were misdiagnosed initially as malignant lesion based on C-T findings. Those C-T patterns have been found to correlate with certain histologic and morphologic alternation in tumor anatomy. Close correlation with pathological findings of tumor necrosis, cystic changes and hemorrhage was noted.

Therapeutic Results of Chemonucleolysis in Patients with Herniated Lumbar Discs

We had experienced 60 cases of chemonucleolysis with Discase(R)(chymopapain for injection) under careful patient selection of herniated lumbar discs and had followed up thereafter at least 3 months since July, 1984. Therapeutic results were generally favorable, with 90% of patients achieving either excellent or good(satisfactory) results. Three patients only had poor or failure results. There was no major anaphylatic reaction and no serious neurologic complications. Back spasm and stiffness/soreness were the most frequently encountered complications.